• Product NameSLC12A6 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SLC12A6 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human Solute carrier family 12 (potassium/chloride transporters), member 6
• Target NameSLC12A6
• Alternative Names    KCC3; ACCPN; KCC3A; KCC3B
• Accession No. Swiss-Prot#: Q9UHW9
  NCBI Gene ID: 9990
  Gene Accssion: NP_598408
• UniprotQ9UHW9
• Gene ID9990;
• Concentration 1.2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.

• Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #37030 at dilution 1/40.
• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #37030 at dilution 1/40.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting