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SOCS7 Antibody

37039
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  Catalog No. Package Size Price
37039 100ul $279.00

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Description
  • Product Name SOCS7 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antigen affinity purification.
  • Applications IHC
  • Species Reactivity Hu
  • Specificity The antibody detects endogenous levels of total SOCS7 protein.
  • Immunogen Type Peptide
  • Immunogen Description Synthetic peptide corresponding to residues near the N terminal of human suppressor of cytokine signaling 7
  • Target Name SOCS7
  • Alternative Names NAP4; NCKAP4
  • Accession No. Swiss-Prot#: O14512
    NCBI Gene ID: 30837
    Gene Accssion: NP_055413
  • Concentration 1.1mg/ml
  • Formulation Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
  • Storage Store at -20˚C
Application Details

Immunohistochemistry: 1:50-1:200

Images
  • SOCS7 Antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #37039 at dilution 1/30.

  • SOCS7 Antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using #37039 at dilution 1/30.

Background
The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
    Please let us know if you have published research using #37039 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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