• Product NameSIPA1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SIPA1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human signal-induced proliferation-associated 1
• Target NameSIPA1
• Alternative Names    SPA1
• Accession No. Swiss-Prot#: Q96FS4
  NCBI Gene ID: 6494
  Gene Accssion: NP_006738.3
• UniprotQ96FS4
• Gene ID6494;
• Concentration 0.9mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #37252 at dilution 1/30.
• Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using #37252 at dilution 1/30.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting