• Product NameSSB Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total SSB protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human Sjogren syndrome antigen B (autoantigen La)
• Target NameSSB
• Alternative Names    La; LARP3
• Accession No. Swiss-Prot#: P05455
  NCBI Gene ID: 6741
  Gene Accssion: NP_003133.1
• UniprotP05455
• Gene ID6741;
• Concentration 0.6mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus.

• Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #37254 at dilution 1/20.
• Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using #37254 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting