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DEFA1/3 Antibody

37410
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  Catalog No. Package Size Price
37410 100ul $279.00

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Description
  • Product Name DEFA1/3 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antigen affinity purification.
  • Applications IHC
  • Species Reactivity Hu
  • Specificity The antibody detects endogenous levels of total DEFA1/3 protein.
  • Immunogen Type Peptide
  • Immunogen Description Synthetic peptide corresponding to a region derived from internal residues of human defensin, alpha 1/3
  • Target Name DEFA1-3
  • Alternative Names HP1; MRS; DEF1; HP-1; DEFA2; HNP-1/HP3; DEF3; HNP3; HP-3; HNP-3
  • Accession No. Swiss-Prot#: P59665/P59666
    NCBI Gene ID: 1667/1668
    Gene Accssion: NP_004075/NP_005208
  • Concentration 2.7mg/ml
  • Formulation Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
  • Storage Store at -20˚C
Application Details

Immunohistochemistry: 1:25-1:100

Images
  • DEFA1/3 Antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37410 at dilution 1/30.

  • DEFA1/3 Antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #37410 at dilution 1/30.

Background
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Defensin, alpha Several alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8.
    Please let us know if you have published research using #37410 so that we can cite your reference.
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    Protocol
    Browsing historyclear
    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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