• Product NameSIGLEC6 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SIGLEC6 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human sialic acid binding Ig-like lectin 6
• Target NameSIGLEC6
• Alternative Names    CD327; CD33L; OBBP1; CD33L1; CD33L2; CDW327
• Accession No. Swiss-Prot#: O43699
  NCBI Gene ID: 946
  Gene Accssion: NP_001171018
• UniprotO43699
• Gene ID946;
• SDS-PAGE MW 50kd
• Concentration 3mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  Immunohistochemistry: 1:50-1:200

The?SIGLEC6?gene to 19q13.3, which is where the CD33 gene is located. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.

• Gel: 8%SDS-PAGE
  Lysates (from left to right): Human placenta tissue
  Amount of lysate: 40ug per lane
  Primary antibody: 1/1000 dilution
  Secondary antibody dilution: 1/8000
  Exposure time: 1 minute
• Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37473 at dilution 1/70.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting