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GABRA1 Antibody

37583
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  Catalog No. Package Size Price
37583 100ul $279.00

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Description
  • Product Name GABRA1 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antigen affinity purification.
  • Applications WB IHC
  • Species Reactivity Hu
  • Specificity The antibody detects endogenous levels of total GABRA1 protein.
  • Immunogen Type Peptide
  • Immunogen Description Synthetic peptide corresponding to a region derived from internal residues of human gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • Target Name GABRA1
  • Alternative Names EJM; ECA4; EJM5
  • Accession No. Swiss-Prot#: P14867
    NCBI Gene ID: 2554
    Gene Accssion: NP_000797
  • SDS-PAGE MW 52kd
  • Concentration 1.7mg/ml
  • Formulation Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
  • Storage Store at -20˚C
Application Details

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100

Images
  • GABRA1 Antibody - SAB | Signalway Antibody

    Gel: 8%SDS-PAGE
    Lysates (from left to right): Human stomach cancer tissue and LoVo cell
    Amount of lysate: 40ug per lane
    Primary antibody: 1/200 dilution
    Secondary antibody dilution: 1/8000
    Exposure time: 10 minutes

  • GABRA1 Antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37583 at dilution 1/30.

Background
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene
    Please let us know if you have published research using #37583 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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