• Product NameITPR1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total ITPR1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human inositol 1,4,5-trisphosphate receptor, type 1
• Target NameITPR1
• Alternative Names    ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1
• Accession No. Swiss-Prot#: Q14643
  NCBI Gene ID: 3708
  Gene Accssion: NP_001093422
• UniprotQ14643
• Gene ID3708;
• Concentration 2.1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

• Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #37665 at dilution 1/40.
• Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37665 at dilution 1/40.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting