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KCNMB4 Antibody

37680
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  Catalog No. Package Size Price
37680 100ul $279.00

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Description
  • Product Name KCNMB4 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antigen affinity purification.
  • Applications WB IHC
  • Species Reactivity Hu Ms
  • Specificity The antibody detects endogenous levels of total KCNMB4 protein.
  • Immunogen Type Peptide
  • Immunogen Description Synthetic peptide corresponding to residues near the N terminal of human potassium large conductance calcium-activated channel, subfamily M, beta member 4
  • Target Name KCNMB4
  • Alternative Names Hbeta4; K(VCA)beta-4; KCMB4; KCNMB4; Slo-beta-4
  • Accession No. Swiss-Prot#: Q86W47
    NCBI Gene ID: 27345
    Gene Accssion: NP_055320
  • SDS-PAGE MW 24kd
  • Concentration 2.9mg/ml
  • Formulation Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
  • Storage Store at -20˚C
Application Details

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200

Images
  • KCNMB4 Antibody - SAB | Signalway Antibody

    Gel: 10%SDS-PAGE
    Lysates (from left to right): Mouse brain tissue
    Amount of lysate: 40ug per lane
    Primary antibody: 1/500 dilution
    Secondary antibody dilution: 1/8000
    Exposure time: 1 minute

  • KCNMB4 Antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #37680 at dilution 1/40.

Background
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.
    Please let us know if you have published research using #37680 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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