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P2RX3 Antibody

37787
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  Catalog No. Package Size Price
37787 100ul $279.00

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Description
  • Product Name P2RX3 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antigen affinity purification.
  • Applications WB IHC
  • Species Reactivity Hu
  • Specificity The antibody detects endogenous levels of total P2RX3 protein.
  • Immunogen Type Peptide
  • Immunogen Description Synthetic peptide corresponding to residues near the C terminal of human purinergic receptor P2X, ligand-gated ion channel, 3
  • Target Name P2RX3
  • Alternative Names P2X3
  • Accession No. Swiss-Prot#: P56373
    NCBI Gene ID: 5024
    Gene Accssion: NP_002550
  • SDS-PAGE MW 44kd
  • Concentration 2.9mg/ml
  • Formulation Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
  • Storage Store at -20˚C
Application Details

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100

Images
  • P2RX3 Antibody - SAB | Signalway Antibody

    Gel: 8%SDS-PAGE
    Lysates (from left to right): Human bladder and bladder transitional cell carcinoma tissue
    Amount of lysate: 40ug per lane
    Primary antibody: 1/250 dilution
    Secondary antibody dilution: 1/8000
    Exposure time: 10 minutes

  • P2RX3 Antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37787 at dilution 1/50.

Background
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
    Please let us know if you have published research using #37787 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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