• Product NameSASH1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total SASH1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of human SAM and SH3 domain containing 1
• Target NameSASH1
• Alternative Names    SH3D6A; dJ323M4; dJ323M4.1
• Accession No. Swiss-Prot#: O94885
  NCBI Gene ID: 23328
  Gene Accssion: NP_056093/O94885
• UniprotO94885
• Gene ID23328;
• Concentration 1.4mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:25-1:100

SASH1 (SAM and SH3 domain-containing protein 1), also known as PEPE1 (Proline-glutamate repeat-containing protein), is a 1247 amino acid protein that is significantly downregulated in the majority of primary breast tumor tissues, breast cancer cell lines, lung and thyroid tumors, as well as in certain colon carcinomas. It has been hypothesized that its expression is suppressed not due to mutation of the SASH1 gene, but instead via other mechanisms, such as promoter methylation.

• Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue using #37895 at dilution 1/20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting