• Product NameIGF1R antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total IGF1R protein.
• Immunogen TypePeptide
• Immunogen DescriptionA synthetic peptide of human IGF1R (NP_000866.1).
• Target NameIGF1R
• Alternative Names    IGF1R;CD221;IGFIR;IGFR;JTK13
• Accession No. Uniprot:P08069
  GeneID:3480
• UniprotP08069
• Gene ID3480
• SDS-PAGE MW 100KDa
• Concentration 1.0mg/ml
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

• Western blot analysis of extracts of various cell lines, using IGF1R antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting