• Product NameNUMBL antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB
• Species ReactivityHuman,Mouse
• SpecificityThe antibody detects endogenous level of total NUMBL protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human NUMBL.
• Target NameNUMBL
• Alternative Names    CAG3A; CTG3a; NBL; NUMB-R; NUMBLIKE; NUMBR; TNRC23;
• Accession No. Swiss-Prot#: Q9Y6R0
  NCBI Gene ID: 9253
• UniprotQ9Y6R0
• Gene ID9253;
• SDS-PAGE MW 65kd
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

Numb-like (Numbl or Nbl) binds Notch and is an intracellular modulator of Notch signaling pathway. Numbl contains a phosphotyrosine binding (PTB) domain that could bind the Y682 motif present in the cytoplasmic tail of APP. Deduced molecular weight of Numbl is 72 kDa.

• Western blot analysis of extracts of Mouse kidney cells, using NUMBL .

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting