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Human Rage ELISA Kit

EK5367
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  Catalog No. Package Size Price
EK5367 96T $599.00

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Description
  • Product Name Human Rage ELISA Kit
  • Specificity Human
  • Crossing Reactivity There is no detectable cross-reactivity with other relevant proteins.
  • Immunogen Type NSO,Q24-A344
  • Alternative Names cDNA FLJ56412, highly similar to Advanced glycosylation end product-specific receptor;
  • Accession No. B4DNX3
Application Details

sensitivity:10pg ml
Detect Range:78pg ml-5000pg ml
sample_type:cell culture supernates cell lysates tissue homogenates serum and plasma (heparin EDTA).
capture_antibody:monoclonal antibody from mouse
detection_antibody:polyclonal antibody from goat
gene_name:AGER
protein_name:Advanced glycosylation end product-specific receptor
gene_full_name:advanced glycosylation end product-specific receptor
tissue_specificity:
sequence_similarities:
tmb_incubation:20-25min
research_category:neuroscience|neurology process|neurodegenerative disease|alzheimer"s disease|amyloid|sensory system|visual system|cardiovascular|atherosclerosis|diabetes associated|vascular inflammation|inflammatory mediators

Product Description
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Rage
Background
protein_function:
RAGE, the Receptor for Advanced Glycation Endproducts, is a 35kD transmembrane receptor of the immunoglobulin super family. It is also known as ??AGER??. AGER gene is mapped to chromosome 6p21.3 by mapping by contiguous cosmids and YAC clones and by fluorescence in situ hybridization. The expression of RAGE is particularly increased in neurons close to deposits of amyloid beta peptide and to neurofibrillary tangles. RAGE has been linked to several chronic diseases, which are thought to result from vascular damage. The pathogenesis is hypothesized to include ligand binding upon which RAGE signals activation of the nuclear factor kappa B(NF-kappaB).
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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