• Product NameMouse Kremen-1 ELISA Kit
• SpecificityMouse
• Crossing ReactivityThere is no detectable cross-reactivity with other relevant proteins.
• Immunogen TypeNSO,A20-G395
• Alternative Names    Kremen protein 1; Dickkopf receptor; Kringle domain-containing transmembrane protein 1; Kringle-containing protein marking the eye and the nose; Kremen1; Kremen;
• Accession No. Q99N43
• UniprotQ99N43
• Gene ID84035;
• Cell Localization Membrane; Single-pass type Imembrane protein.

• sensitivity:10pg ml
  Detect Range:125pg ml-8000pg ml
  sample_type:cell culture supernates cell lysates tissue homogenates serum and plasma (heparin EDTA).
  capture_antibody:
  detection_antibody:
  gene_name:Kremen1
  protein_name:Kremen protein 1
  gene_full_name:Kremen protein 1
  tissue_specificity: In the adult widely expressed with highlevels in heart lung kidney skeletal muscle and testis..
  sequence_similarities:
  tmb_incubation:15-20min
  research_category:signal transduction|cytoskeleton / ecm|cell adhesion|cadherins|stem cells|signaling pathways|wnt|surface molecules

• Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Kremen-1

protein_function: Receptor for Dickkopf protein. Cooperates with Dickkopfto block Wnt,beta-catenin signaling (By similarity)..
Kremen protein 1 is a protein that in humans is encoded by the KREMEN1 gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT),beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting