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Mouse Meprinbeta,MEP1B ELISA Kit

EK5789
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  Catalog No. Package Size Price
EK5789 96T $599.00

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Description
  • Product Name Mouse Meprinbeta,MEP1B ELISA Kit
  • Specificity Mouse
  • Crossing Reactivity There is no detectable cross-reactivity with other relevant proteins.
  • Immunogen Type NSO,L21-S594
  • Alternative Names Meprin A subunit beta; Endopeptidase-2; Meprin B; Mep-1b
  • Accession No. Q61847
Application Details

sensitivity:10pg ml
Detect Range:0.156ng ml-10ng ml
sample_type:cell culture supernates cell lysates tissue serum plasma (heparin EDTA).
capture_antibody:monoclonal antibody from rat
detection_antibody:polyclonal antibody from goat
gene_name:Mep1b
protein_name:Meprin A subunit beta
gene_full_name:meprin 1 beta
tissue_specificity:
sequence_similarities:
tmb_incubation:20-25min
research_category:

Product Description
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Meprinbeta,MEP1B
Background
protein_function:
Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and,or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.
    Please let us know if you have published research using #EK5789 so that we can cite your reference.
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
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    • RbRabbit
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