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FKHR(Phospho-Ser256) Antibody #11115

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Catalog No. Package Size Price Quantity
50ul $189.00
100ul $279.00
Availability:Yes
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Description
  • Product NameFKHR(Phospho-Ser256) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
  • ApplicationsWB IHC IF
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of FKHR only when phosphorylated at serine 256.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionA synthesized peptide derived from human FOXO1A around the phosphorylation site of Ser256.
  • Target NameFKHR
  • ModificationPhospho
  • Alternative Names    FKHR; FOXO1;
  • Accession No. Swiss-Prot: Q12778
    NCBI Protein: NP_002006.2
  • Calculated MW 70kDa
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Translocation of forkhead box O1 to the nuclear periphery induces histone modifications that regulate transcriptional repression of PCK1 in HepG2 cells.In Genes Cells on 2015 Apr by Tamaki Arai, Fumi Kano et al..PMID: 25736587, , (2015),
PMID: 25736587
Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K–Akt signaling pathways. In Regul Pept on 2013 Feb 10 by Libing Ma, Jinxiu Li, et al..PMID: 23327998, , (2013),
PMID: 23327998
Activation of Akt/FoxO and inactivation of MEK/ERK pathways contribute to induction of neuroprotection against transient global cerebral ischemia by delayed hypoxic postconditioning in adult rats.In Neuropharmacology on 2012 Oct by Zhan L, Li D,et al..PMID:22749925, , (2012),
PMID: 22749925
Zhan Lixuan, Tao Wang, Wen Li Activation of AKT/FoxO signaling pathway contributes to induction of neuroprotection against transient global cerebral ischemia by hipoxic pre-conditioning in adult rats., Journal of Neurochemistry, 114(3):897-908 (2010),
PMID: 20492357
View All Published Papers Activation of Akt/FoxO signaling pathway contributes to induction of neuroprotection against transient global cerebral ischemia by hypoxic pre-conditioning in adult rats.In J Neurochem on 2010 Aug by Zhan L, Wang T, et al..PMID:20492357, , (2010),
PMID: 20492357
Please let us know if you have published research using #11115 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep