• Product NameDocetaxel trihydrate
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityDocetaxel trihydrate(Taxotere trihydrate), an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules.
• Target NameBcr-Abl antagonist; Microtubule Associated inhibitor
• CAS No. 148408-66-6
• Calculated MW 861.95
• Formulation C43H59NO17
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O.O.O.O
  Pathways:Angiogenesis; Cytoskeletal Signaling
  Receptor:Bcl-2; Tubulin β-1 chain
  Boling pt:1016.9C
  Melting pt:186-192C
  Solubility:Ethanol: 100 mg/mL (116.01 mM); DMSO: 100 mg/mL (116.01 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Matesanz R, et al. Chem Biol. 2008 Jun;15(6):573-85.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting