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Dacogen #S1508

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Catalog No. Package Size Price Quantity
10mg $57.00
50mg $91.00
100mg $128.00
200mg $180.00
Availability:The lead time is currently 7-30 days.
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Description
  • Product NameDacogen
  • Brief DescriptionInhibitors
  • Purification99.00%
  • Biological ActivityDecitabine is indicated for treatment of patients with myelodysplastic syndrome (MDS). It is a chemical analogue of cytidine, a nucleoside present in DNA and RNA. Cells in the presence of Decitabine incorporate it into DNA during replication and RNA during transcription. The incorporation of Decitabine into DNA or RNA inhibits methyltransferase thereby causing demethylation in that sequence. This adversely affects the way that cell regulatory proteins are able to bind to the DNA/RNA substrate.
  • Target NameDNA Methyltransferase inhibitor
  • CAS No. 2353-33-5
  • Calculated MW 228.21
  • Formulation C8H12N4O4
  • Storage 3 years -20˚C powder;2 years -80˚C in solvent;
Product Description
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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep