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SB525334

S1763
Review: comment rank 5 pdf
  Catalog No. Package Size Price
S1763-1 5mg $57.00
S1763-2 10mg $91.00
S1763-3 25mg $165.00
S1763-4 100mg $538.00

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Description
  • Product Name SB525334
  • Brief Description Inhibitors
  • Purification 98.39%
  • Biological Activity SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM in a cell-free assay, is 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.
  • Target Name TGF-beta/Smad inhibitor
  • CAS No. 356559-20-1
  • Calculated MW 343.42
  • Formulation C21H21N5
  • Storage 3 years -20˚C powder;2 years -80˚C in solvent;
Images
  • SB525334 - SAB | Signalway Antibody


Product Description

Research Area:Other
SMILES:CC1=CC=CC(=N1)C1=C(N=C(N1)C(C)(C)C)C1=CC2=NC=CN=C2C=C1
Pathways:Stem Cells
Receptor:TGFβR1(ALK5)
Boling pt:
Melting pt:
Solubility:Ethanol: 68 mg/mL (198.0 mM); DMSO: 68 mg/mL (198.0 mM)
Appearance:Yellow Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

Regerences

1. Grygielko ET, et al. J Pharmacol Exp Ther, 2005, 313(3), 943-951.

    Please let us know if you have published research using #S1763 so that we can cite your reference.
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      Application:
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    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
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