• Product NameMTHFS Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu, Ms
• SpecificityThe antibody detects endogenous levels of total MTHFS protein.
• Immunogen TypePeptide
• Immunogen DescriptionFusion protein of human MTHFS
• Target NameMTHFS
• Alternative Names    HsT19268
• Accession No. Swiss-Prot#:P49914
  NCBI Gene ID:10588
  Gene Accssion:BC019921
• UniprotP49914
• Gene ID10588;
• Concentration 1.7
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• IHC dilution:1: 50-300
  

The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.

• The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 47363(MTHFS Antibody) at dilution 1/50.(Original magnification: 200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting