• Product NameWNK4 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu, Ms, Rt
• SpecificityThe antibody detects endogenous levels of total WNK4 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide of human WNK4
• Target NameWNK4
• Alternative Names    PHA2B; PRKWNK4
• Accession No. Swiss-Prot#:Q96J92
  NCBI Gene ID:65266
  Gene Accssion:NP_115763
• UniprotQ96J92
• Gene ID65266;
• Concentration 0.8
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• IHC dilution:1: 25-100
  

This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

• The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 47499(WNK4 Antibody) at dilution 1/25.(Original magnification: 200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting