• Product NameIZUMO1R Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total IZUMO1R protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide of human IZUMO1R
• Target NameIZUMO1R
• Alternative Names    JUNO; FOLR4; Folbp3
• Accession No. Swiss-Prot#:A6ND01
  NCBI Gene ID:390243
  Gene Accssion:NP_001186135
• UniprotA6ND01
• Gene ID390243;
• Concentration 1.2
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• IHC dilution:1: 25-100
  

Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.

• The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using 47763(IZUMO1R Antibody) at dilution 1/40.(Original magnification: 200)
• The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 47763(IZUMO1R Antibody) at dilution 1/40.(Original magnification: 200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting