• Product NamePlexin A1 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.JU50-37
• PurificationProA affinity purified
• ApplicationsWB,ICC,FC
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein
• Alternative Names    NOV antibody
  NOV/plexin A1 protein antibody
  NOVP antibody
  Plexin-A1 antibody
  Plexin1 antibody
  PlexinA1 antibody
  PLXA1_HUMAN antibody
  PLXN1 antibody
  Plxna1 antibody
  PLXNA1 protein antibody
  Semaphorin receptor NOV antibody
  
• Accession No. Swiss-Prot#:Q9UIW2
• UniprotQ9UIW2
• Gene ID5361;
• Calculated MW 211 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• 
  
  ICC: 1:50-1:200
  
  FC: 1:50-1:100

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

• ICC staining Plexin A1 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
• Flow cytometric analysis of LOVO cells with Plexin A1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting