• Product NameCXCR5 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.JB11-40
• PurificationProA affinity purified
• ApplicationsWB,IHC,FC
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein
• Alternative Names    BLR 1 antibody
  BLR1 antibody
  Burkitt lymphoma receptor 1 antibody
  Burkitt lymphoma receptor 1 GTP binding protein antibody
  Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) antibody
  C X C chemokine receptor type 5 antibody
  C-X-C chemokine receptor type 5 antibody
  CD 185 antibody
  CD185 antibody
  CD185 antigen antibody
  Chemokine (C-X-C motif) receptor 5 antibody
  Chemokine C X C motif receptor 5 antibody
  Chemokine CXC motif receptor 5 antibody
  Chemokine receptor 5 antibody
  CXC chemokine receptor type 5 antibody
  CXC R5 antibody
  CXC-R5 antibody
  CXCR 5 antibody
  CXCR-5 antibody
  Cxcr5 antibody
  CXCR5_HUMAN antibody
  MDR 15 antibody
  MDR-15 antibody
  MDR15 antibody
  MGC117347 antibody
  Monocyte derived receptor 15 antibody
  Monocyte-derived receptor 15 antibody
  
• Accession No. Swiss-Prot#:P32302
• UniprotP32302
• Gene ID643;
• Calculated MW 42 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• WB: 1:500-1:1,000
  IHC: 1:50-1:200
  
  
  FC: 1:50-1:100

Burkitt's lymphoma receptor 1 (Blr1) is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G-protein coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B-lymphocyte chemo-attractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B-cell migration into splenic and Peyer's patch follicles. BLC expression in Peyer's patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation.

• Western blot analysis of CXCR5 on Daudi cell using anti-CXCR5 antibody at 1/500 dilution.
• Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-CXCR5 antibody. Counter stained with hematoxylin.
• Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CXCR5 antibody. Counter stained with hematoxylin.
• Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-CXCR5 antibody. Counter stained with hematoxylin.
• Flow cytometric analysis of Daudi cells with CXCR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting