• Product NameBranched-chain-amino-acid aminotransferase, mitochondrial Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Branched-chain-amino-acid aminotransferase, mitochondrial polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Branched-chain-amino-acid aminotransferase, mitochondrial (28-392aa)
• Target NameBranched-chain-amino-acid aminotransferase, mitochondrial
• Alternative Names    Branched-chain-amino-acid aminotransferase, mitochondrial, Placental protein 18, BCATM, BCT2, ECA40, BCAT2
• Accession No. Swiss-Prot#: O15382
• UniprotO15382
• Gene ID587;
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:20 - 1:200

Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids.

[1]"Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis."Yennawar N.H., Islam M.M., Conway M., Wallin R., Hutson S.M.J. Biol. Chem. 281:39660-39671(2006). [2]"Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin." Goto M., Miyahara I., Hirotsu K., Conway M., Yennawar N., Islam M.M., Hutson S.M.J. Biol. Chem. 280:37246-37256(2005). [3]"Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms."Yennawar N.H., Conway M.E., Yennawar H.P., Farber G.K., Hutson S.M.Biochemistry 41:11592-11601(2002).

• Immunohistochemical analysis of paraffin-embedded human skin tissue using #42080 at dilution of 1:100.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting