• Product NameCasein kinase I isoform epsilon Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Casein kinase I isoform epsilon polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Casein kinase I isoform epsilon protein
• Target NameCasein kinase I isoform epsilon
• Alternative Names    CSNK1E, CKI-epsilon, CKIe
• Accession No. Swiss-Prot#: P49674
• UniprotP49674
• Gene ID102800317;1454;
• Calculated MW 45.8kd
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• Western blotting: 1:500 - 1:1000
  

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation.

[1]"Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family."Fish K.J., Cegielska A., Getman M.E., Landes G.M., Virshup D.M.J. Biol. Chem. 270:14875-14883(1995) [2]"Casein kinase I epsilon from HeLa ce

• All lanes : Casein kinase I isoform epsilon antibody at 2ug/mlLane 1 : EC109 whole cell lysateLane 2 : 293T whole cell lysate SecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilution Predicted band size : 45.8 kDa Observed band size: 75kDa

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting