• Product NameLeucine-rich repeat flightless-interacting protein 1 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Leucine-rich repeat flightless-interacting protein 1 polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Leucine-rich repeat flightless-interacting protein 1 protein
• Target NameLeucine-rich repeat flightless-interacting protein 1
• Alternative Names    LRR FLII-interacting protein 1, GC-binding factor 2, TAR RNA-interacting protein, GCF2, TRIP, LRRFIP1
• Accession No. Swiss-Prot#: Q32MZ4
• UniprotQ32MZ4
• Gene ID9208;
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

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  Immunohistochemistry: 1:20 - 1:200

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

[1]Molecular cloning and characterization of a transcription regulator with homology to GC-binding factor.Reed A.L., Yamazaki H., Kaufman J.D., Rubinstein Y., Murphy B.A., Johnson A.C.J. Biol. Chem. 273:21594-21602(1998) [2]TRIP: a novel double strande

• Immunohistochemical analysis of paraffin-embeded human prostate using #42245 at dilution of 1:100.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting