• Product NameRNA-binding protein FUS Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total RNA-binding protein FUS polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human RNA-binding protein FUS protein
• Target NameRNA-binding protein FUS
• Alternative Names    FUS, TLS, 75 kDa DNA-pairing protein, Oncogene FUS, Oncogene TLS, POMp75, Translocated in liposarcoma protein
• Accession No. Swiss-Prot#: P35637
• UniprotP35637
• Gene ID2521;
• Calculated MW 60kd
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• Western blotting: 1:500 - 1:1000
  Immunohistochemistry: 1:20 - 1:200

Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity.

[1] "Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma."Crozat A., Aman P., Mandahl N., Ron D.Nature 363:640-644(1993) [2] "Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by t

• All lanes : RNA-binding protein FUS antibody at 2ug/ml Lane 1 : 293T whole cell lysate Lane 2 : EC109 whole cell lysate Secondary Goat polyclonal to Rabbit IgG at 1/15000 dilution Predicted band size : 60kDa Observed band size: 60kDa
• Immunohistochemical analysis of paraffin-embedded human kidney using #42370 at dilution of 1:100.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting