Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX By similarity. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
[1]Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I.Takeshita S., Kikuno R., Tezuka K., Amann E.Biochem. J. 294:271-278(1993) [2]Periostin secreted by epithelial ovarian carcino