• Product NameKL Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total KL protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human KL
• Target NameKL
• Alternative Names    KLOT; Klotho; Klotho peptide
• Accession No. Swiss-Prot#: Q9UEF7
  Gene ID: 9365
• UniprotQ9UEF7
• Gene ID9365;
• Calculated MW 62kd
• Concentration 0.9mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  

This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.

• Gel: 10%SDS-PAGE
  Lysate: 40 μg
  Lane: Jurkat cells
  Primary antibody: 1/250 dilution
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
  Exposure time: 2 minutes

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting