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AGT Conjugated Antibody

C36739
Review: comment rank 5 pdf
  Catalog No. Package Size Price
C36739-AF350 100ul $399.00
C36739-AF405 100ul $399.00
C36739-AF488 100ul $399.00
C36739-AF555 100ul $399.00
C36739-AF594 100ul $399.00
C36739-AF647 100ul $399.00
C36739-AF680 100ul $399.00
C36739-AF750 100ul $399.00
C36739-Biotin 100ul $399.00

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Description
  • Product Name AGT Conjugated Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Species Reactivity Hu
  • Specificity The antibody detects endogenous levels of total AGT protein.
  • Immunogen Description Synthetic peptide corresponding to a region derived from internal residues of human angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Conjugates Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
  • Excitation Emission AF350: 346nm/442nm
    AF405: 401nm/421nm
    AF488: 493nm/519nm
    AF555: 555nm/565nm
    AF594: 591nm/614nm
    AF647: 651nm/667nm
    AF680: 679nm/702nm
    AF750: 749nm/775nm
  • Alternative Names ANHU, SERPINA8
  • Accession No. Swiss-Prot#:P01019
    NCBI Gene ID:183
    NCBI mRNA#:
    NCBI Protein#:NP_000020
  • Calculated MW 53
  • Concentration
  • Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
  • Storage Store at 4˚Cin dark for 6 months
Application Details

Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Background
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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