• Product NameGZMM Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC WB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total GZMM protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human GZMM
• Target NameGZMM
• Alternative Names    MET1; LMET1
• Accession No. Swiss-Prot#: P51124
  NCBI Gene ID: 3004
• UniprotP51124
• Gene ID3004;
• Calculated MW 28kd
• Concentration 1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1000
  Immunohistochemistry: 1: 20-100

Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.

• Gel: 12%SDS-PAGE
  Lysate: 40 μg, Lane: RAW264.7 cell,
  Primary antibody:GZMM antibody at dilution 1/400 dilution,
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
  Exposure time: 1 minute
• The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using GZMM Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting