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IkB-a(Phospho-Ser32/Ser36) Antibody #11152

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameIkB-a(Phospho-Ser32/Ser36) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC IF
  • Species ReactivityHu Ms
  • SpecificityThe antibody detects endogenous level of IkB-a only when phosphorylated at serine 32/36.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of serine 32/36 (H-D-S(p)-G-L-D-S(p)-M-K) derived from Human IkB-a.
  • Target NameIkB-a
  • ModificationPhospho
  • Alternative Names    I-kappa-B-alpha; IKBA; NF-kappaB inhibitor alpha; NFKBI; NFKBIA
  • Accession No. Swiss-Prot: P25963
    NCBI Protein: NP_065390.1
  • UniprotP25963
  • Gene ID4792;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Vitexin Protects against Dextran Sodium Sulfate-Induced Colitis in Mice and Its Potential Mechanisms. In J Agric Food Chem on 2022 Sep 28 by Jing Zhang, Feilin Liang,et al..PMID: 36124900, , (2022),
PMID: 36124900
Phytoestrogens protect joints in collagen induced arthritis by increasing IgG glycosylation and reducing osteoclast activation.In Int Immunopharmacol on 2020 Mar 12 by Du N, Song L, et al..PMID:32172207, , (2020),
PMID: 32172207
Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-kB signaling and NLRP3 inflammasome . In Eur J Pharmacol on 2020 Sep 15 by Yonger Chen , Yingyu Lu, et al..PMID:32710952, , (2020), , (2020),
PMID: 32710952
Cetuximab enhances oridonin-induced apoptosis through mitochondrial pathway and endoplasmic reticulum stress in laryngeal squamous cell carcinoma cells. In Toxicol In Vitro on 2020 May 12 by Ning Kang, Shijie Cao, et al..PMID:32407876, , (2020),
PMID: 32407876
View All Published Papers Indirect effect of PM1 on endothelial cells via InducIng the release of respiratory Inflammatory cytokInes.In Toxicol In Vitro. On 2019 Jun by Tian G, Wang J,et al..al PMID: 30858030, , (2019),
PMID: 30858030
HMGN2 regulates non-tuberculous mycobacteria survival via modulation of M1 macrophage polarization. In J Cell Mol Med on 2019 Dec by Wang X, Chen S, et al..PMID:31596045, , (2019),
PMID: 31596045
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.In Oxid Med Cell Longev.On 2018 Oct 10 by Jiang H, Gao X et al..PMID:30405874, , (2018),
PMID: 30405874
Inhibition of TPL2 by interferon-α suppresses bladder cancer through activation of PDE4D.In J Exp Clin Cancer Res. On 2018 Nov 27 by Qiang Z, Zhou ZY et al..PMID: 30482227, , (2018),
PMID: 30482227
Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation.In Pharm Biol. On 2018 Dec by Zhang H, Ren QC et al..PMID: 31070535 , , (2018),
PMID: 31070535
Angiotensin II Induces Connective Tissue Growth Factor Expression in Human Hepatic Stellate Cells by a Transforming Growth Factor β-Independent Mechanism.In Sci Rep on 2017 Aug 10 by Ao Li Jingyao Zhang,et al..PMID: 28798388, , (2017),
PMID: 28798388
Rumen-derived lipopolysaccharide enhances the expression of lingual antimicrobial peptide in mammary glands of dairy cows fed a high-concentrate diet.In BMC Vet Res on 2016 Jun 27 by Di Jin, Guangjun Chang et al..PMID: 27350130, , (2016),
PMID: 27350130
Protodioscin ameliorates fructose-induced renal injury via inhibition of the mitogen activated protein kinase pathway.In Phytomedicine on 2016 Nov 15 by Jinyang Shen, Xiaolin Yang et al..PMID:27765371, , (2016),
PMID: 27765371
Inhibitory effects of eugenol on RANKL-induced osteoclast formation via attenuation of NF-k B and MAPK pathways.In Connect Tissue Res on 2015 Jun by Vishwa Deepak , Abe Kasonga et al..PMID:25405641, , (2015),
PMID: 25405641
Piperine alleviates osteoclast formation through the p38/c-Fos/NFATc1 signaling axis.In Biofactors on Nov-Dec 2015 by Vishwa Deepak , Marlena C Kruger et al..PMID: 26627060, , (2015),
PMID: 26627060
Cordycepin Suppresses TNF-α-induced NF-kB Activation by Reducing p65 Transcriptional Activity, Inhibiting IkBα Phosphorylation, and Blocking IKKγ Ubiquitination.In Int Immunopharmacol on 2012 Dec by Zhenghua Ren, Jianhua Cui,et al..PMID:23102662, , (2012),
PMID: 23102662
Cordycepin Suppresses TNF-α-induced NF-kB Activation by Reducing p65 Transcriptional Activity, Inhibiting IkBα Phosphorylation, and Blocking IKKγ Ubiquitination.In Int Immunopharmacol on 2012 Dec by Zhenghua Ren, Jianhua Cui,et al..PMID:23102662, , (2012),
PMID: 23102662
Please let us know if you have published research using #11152 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep