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Lamin A/C antibody

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  Catalog No. Package Size Price
23037 100ul $390.00

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  • Product Name Lamin A/C antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Purified by antigen-affinity chromatography.
  • Applications WB IHC
  • Species Reactivity Hu
  • Immunogen Type Recombinant protein
  • Immunogen Description Recombinant protein fragment contain a sequence corresponding to a region within amino acids 59 and 259 of Lamin A/C
  • Target Name Lamin A/C
  • Accession No. NCBI Gene ID: 4000
    NCBI mRNA#: NM_005572
    NCBI Protein#: NP_005563
  • Concentration 1mg/ml
  • Formulation Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
  • Storage Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Application Details

Predicted MW: 65kd
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:250

  • Lamin A/C antibody - SAB | Signalway Antibody

    Sample (20 ug )
    A: HeLa Nucleus
    10% SDS PAGE
    Primary antibody diluted at 1: 3000

  • Lamin A/C antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded H441 Xenograft, using Lamin A/C antibody at 1: 100 dilution.


The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq]

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      Species Reactivity:
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