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CD26 Conjugated Antibody

C49506
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  Catalog No. Package Size Price
C49506-AF350 100ul $399.00
C49506-AF405 100ul $399.00
C49506-AF488 100ul $399.00
C49506-AF555 100ul $399.00
C49506-AF594 100ul $399.00
C49506-AF647 100ul $399.00
C49506-AF680 100ul $399.00
C49506-AF750 100ul $399.00
C49506-Biotin 100ul $399.00

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Description
  • Product Name CD26 Conjugated Antibody
  • Host Species Rabbit
  • Clonality Monoclonal
  • Species Reactivity Hu, Ms, Rt
  • Immunogen Description recombinant protein
  • Conjugates Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
  • Excitation Emission AF350: 346nm/442nm
    AF405: 401nm/421nm
    AF488: 493nm/519nm
    AF555: 555nm/565nm
    AF594: 591nm/614nm
    AF647: 651nm/667nm
    AF680: 679nm/702nm
    AF750: 749nm/775nm
  • Alternative Names CD26 antigen antibody
    ADA-binding protein antibody
    ADABP antibody
    ADCP 2 antibody
    ADCP-2 antibody
    ADCP2 antibody
    Adenosine deaminase complexing protein 2 antibody
    CD 26 antibody
    CD26 antibody
    CD26 antigen 3 antibody
    Dipeptidyl peptidase 4 antibody
    Dipeptidyl peptidase 4 soluble form antibody
    Dipeptidyl peptidase IV antibody
    Dipeptidyl peptidase IV membrane form antibody
    Dipeptidyl peptidase IV soluble form antibody
    Dipeptidyl peptidase, intestinal antibody
    Dipeptidylpeptidase 4 antibody
    Dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2) antibody
    Dipeptidylpeptidase IV antibody
    DPP 4 antibody
    DPP IV antibody
    DPP IV estoenzyme antibody
    DPP4 antibody
    DPP4_HUMAN antibody
    DPPIV antibody
    Intestinal dipeptidyl peptidase antibody
    T cell activation antigen CD26 antibody
    T-cell activation antigen CD26 antibody
    TP 103 antibody
    TP103 antibody
  • Accession No. Swiss-Prot#:P27487
  • Calculated MW 110 kDa
  • Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
  • Storage Store at 4˚C in dark for 6 months
Application Details

Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Background
CD26 (dipeptidylpeptidase 4, adenosine deaminase complexing protein 2, ADABP, ADCP2, DPPIV, TP103) is a membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. CD26 has an essential role in immune regulation as a T cell activation molecule and a regulator of chemokine function. CD26 associates with CXCR4 and gp120 and may influence the pathophysiology of HIV infection. Adenosine deaminase (ADA) colocalizing with adenosine receptors on dendritic cells are able to interact with CD26 expressed on lymphocytes. This costimulatory signal in the immunological synapse leads to an increase in the production of the T helper 1 and proinflammatory cytokines IFN-gamma, TNF-alpha, and IL-6. CD26 plays a role in the pathogenesis and behavior of human cancers, including solid tumors and hematological malignancies. CD26-caveolin-1 interaction plays a role in the up-regulation of CD86 on TT-loaded monocytes and subsequent engagement with CD28 on T cells, leading to antigen-specific T cell activation.
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
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