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Approved Drug Library #L1000

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Catalog No. Package Size Price Quantity
L1000 100ul*10mM inquiry
Availability:Yes
 
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Description
  • Product NameApproved Drug Library
  • Brief DescriptionTraditional de novo drug discovery and development involves an HTS campaign for de novo candidate hits and requires highly specialized screening facilities and compound libraries containing several million compounds.It is a time consuming and expensive process. As the regulation for drug safety and efficacy is increasingly getting complex, the cost of developing new drugs is keeping skyrocket. Drug repositioning, also known as old drugs for new uses, is an effective strategy to find new indications for existing drugs and has recently drawn attention and has led to several blockbuster drugs because of its high efficiency and low-cost. High-content screens, new biomarkers, noninvasive imaging techniques, and advanced in bioinformatics have created new opportunities for pursuing novel indications for approved compounds. Approved drugs all have known and well-characterized bioactivities, safety and bioavailability -C properties which could dramatically accelerate drug development and optimization. Hits from this set will provide a significant head start in any drug optimization program. In addition, a growing number of compounds have been identified from this library that can functionally replace reprogramming transcription factors, enhance efficiency of iPSC generation and accelerate the reprogramming process by single use or a combination of several molecules.
  • Storage Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcodeShipped with blue ice; Stable for One year as powder, 6 months at - 20 ˚ C in DMSO or 12months at -80 ˚ C in DMSO
Application Details
Product Description

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep