• Product NameSPRED1 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityMouse
• Immunogen DescriptionRecombinant fusion protein of human SPRED1 (NP_689807.1).
• Alternative Names    SPRED1; NFLS; PPP1R147; hSpred1; spred-1; sprouty related EVH1 domain containing 1
• Accession No. Swiss-Prot#:Q7Z699
  NCBI Gene ID:161742
• UniprotQ7Z699
• Gene ID161742;
• Calculated MW 50kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).

• Western blot analysis of extracts of mouse brain, using SPRED1 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting