• Product NameCLDN17 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC,IF
• Species ReactivityMouse,Rat
• Immunogen DescriptionA synthetic synthetic peptide of human CLDN17 (NP_036263.1).
• Alternative Names    CLDN17; claudin-17
• Accession No. Swiss-Prot#:P56750
  NCBI Gene ID:26285
• UniprotP56750
• Gene ID26285;
• Calculated MW 29kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IHC 1:50 - 1:100
  IF 1:50 - 1:100

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11.

• Western blot analysis of extracts of various cell lines, using CLDN17 at 1:1000 dilution.
• Immunohistochemistry of paraffin-embedded mouse kidney using CLDN17 at dilution of 1:100 (40x lens).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting