• Product NameMANBA Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse
• Immunogen DescriptionRecombinant fusion protein of human MANBA (NP_005899.3).
• Alternative Names    MANBA; MANB1; beta-mannosidase
• Accession No. Swiss-Prot#:O00462
  NCBI Gene ID:4126
• UniprotO00462
• Gene ID4126;
• Calculated MW 101kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:200 - 1:2000
  IHC 1:50 - 1:200

This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement.

• Western blot analysis of extracts of various cell lines, using MANBA at 1:1000 dilution.
• Immunohistochemistry of paraffin-embedded human liver cancer using MANBA at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human thyroid cancer using MANBA at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human colon carcinoma using MANBA at dilution of 1:100 (40x lens).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting