• Product NameKIF7 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman
• Immunogen DescriptionRecombinant fusion protein of human KIF7 (NP_940927.2).
• Alternative Names    KIF7; ACLS; AGBK; HLS2; JBTS12; UNQ340; kinesin family member 7
• Accession No. Swiss-Prot#:Q2M1P5
  NCBI Gene ID:374654
• UniprotQ2M1P5
• Gene ID374654;
• Calculated MW 150kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:200 - 1:2000

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

• Western blot analysis of extracts of various cell lines, using KIF7 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting