• Product NameRLIM Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman,Mouse
• Immunogen DescriptionRecombinant fusion protein of human RLIM (NP_057204.2).
• Alternative Names    RLIM; MRX61; NY-REN-43; RNF12; E3 ubiquitin-protein ligase RLIM
• Accession No. Swiss-Prot#:Q9NVW2
  NCBI Gene ID:51132
• UniprotQ9NVW2
• Gene ID51132;
• Calculated MW 75kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.

• Western blot analysis of extracts of various cell lines, using RLIM at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting