• Product NameTHEM4 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IF
• Species ReactivityHuman,Mouse
• Immunogen DescriptionRecombinant fusion protein of human THEM4 (NP_444283.2).
• Alternative Names    THEM4;CTMP
• Accession No. Uniprot:Q5T1C6
  GeneID:117145
• UniprotQ5T1C6
• Gene ID117145
• Calculated MW 25kDa/27kDa
• SDS-PAGE MW 25kDa/27kDa
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IF 1:50 - 1:200

Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.

• Western blot analysis of extracts of various cell lines, using THEM4 antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting