• Product NamePGAM5 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human PGAM5 (NP_612642.2).
• Alternative Names    PGAM5;BXLBV68
• Accession No. Uniprot:Q96HS1
  GeneID:192111
• UniprotQ96HS1
• Gene ID192111
• Calculated MW 32kDa
• SDS-PAGE MW 28KDa/32KDa
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200

Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.

• Western blot analysis of extracts of various cell lines, using PGAM5 antibody.
• Western blot analysis of extracts of various cell lines, using PGAM5 antibody.
• Immunohistochemistry of paraffin-embedded human tonsil using PGAM5 Rabbit pAb.
• Immunohistochemistry of paraffin-embedded human liver cancer using PGAM5 Rabbit pAb.
• Immunohistochemistry of paraffin-embedded human colon carcinoma using PGAM5 Rabbit pAb.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting