• Product NameHPS4 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IF
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthetic peptide of human HPS4 (NP_690054.1).
• Alternative Names    HPS4; BLOC3S2; LE; Hermansky-Pudlak syndrome 4 protein
• Accession No. Swiss-Prot#:Q9NQG7
  NCBI Gene ID:89781
• UniprotQ9NQG7
• Gene ID89781;
• Calculated MW 115kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IF 1:50 - 1:200

This gene encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in this gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism. Alternative splicing results in multiple transcript variants.

• Western blot analysis of extracts of various cell lines, using HPS4 at 1:1000 dilution.
• Immunofluorescence analysis of C6 cells using HPS4 at dilution of 1:100. Blue: DAPI for nuclear staining.
• Immunofluorescence analysis of L929 cells using HPS4 at dilution of 1:100. Blue: DAPI for nuclear staining.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting