• Product NameSOSTDC1 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human SOSTDC1 (NP_056279.1).
• Alternative Names    SOSTDC1; CDA019; DAND7; ECTODIN; USAG1; sclerostin domain containing 1
• Accession No. Swiss-Prot#:Q6X4U4
  NCBI Gene ID:25928
• UniprotQ6X4U4
• Gene ID25928;
• Calculated MW 26kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.

• Western blot analysis of extracts of various cell lines, using SOSTDC1 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting