• Product NameMXD4 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityMouse
• Immunogen DescriptionRecombinant fusion protein of human MXD4 (NP_006445.1).
• Alternative Names    MXD4; MAD4; MST149; MSTP149; bHLHc12; max dimerization protein 4
• Accession No. Swiss-Prot#:Q14582
  NCBI Gene ID:10608
• UniprotQ14582
• Gene ID10608;
• Calculated MW 30kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.

• Western blot analysis of extracts of mouse lung, using MXD4 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting