• Product NameBLOC1S3 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsIHC,IF
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human BLOC1S3 (NP_997715.1).
• Alternative Names    BLOC1S3; BLOS3; HPS8; RP; biogenesis of lysosomal organelles complex 1 subunit 3
• Accession No. Swiss-Prot#:Q6QNY0
  NCBI Gene ID:388552
• UniprotQ6QNY0
• Gene ID388552;
• Calculated MW Refer to figures
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• IHC 1:50 - 1:200
  IF 1:50 - 1:200

This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.

• Immunohistochemistry of paraffin-embedded human uterine cancer using BLOC1S3 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded mouse kidney using BLOC1S3 at dilution of 1:100 (40x lens).
• Immunofluorescence analysis of NIH-3T3 cells using BLOC1S3 at dilution of 1:100. Blue: DAPI for nuclear staining.
• Immunofluorescence analysis of U-2 OS cells using BLOC1S3 at dilution of 1:100. Blue: DAPI for nuclear staining.
• Immunohistochemistry of paraffin-embedded mouse testis using BLOC1S3 at dilution of 1:100 (40x lens).
• Immunofluorescence analysis of C6 cells using BLOC1S3 at dilution of 1:100. Blue: DAPI for nuclear staining.
• Immunofluorescence analysis of NIH-3T3 cells using BLOC1S3 at dilution of 1:100. Blue: DAPI for nuclear staining.
• Immunofluorescence analysis of U-2 OS cells using BLOC1S3 at dilution of 1:100. Blue: DAPI for nuclear staining.
• Immunohistochemistry of paraffin-embedded human colon using BLOC1S3 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human colon carcinoma using BLOC1S3 at dilution of 1:100 (40x lens).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting