• Product NameERCC8 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityMouse
• Immunogen DescriptionA synthetic synthetic peptide of human ERCC8 (NP_000073.1).
• Alternative Names    ERCC8; CKN1; CSA; UVSS2; DNA excision repair protein ERCC-8
• Accession No. Swiss-Prot#:Q13216
  NCBI Gene ID:1161
• UniprotQ13216
• Gene ID1161;
• Calculated MW 44kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene.

• Western blot analysis of extracts of mouse testis, using ERCC8 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting