• Product NameMYCN Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total MYCN protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide corresponding to internal residues of human MYCN
• Target NameMYCN
• Alternative Names    NMYC; ODED; MODED; N-myc; bHLHe37
• Accession No. Swiss-Prot:P04198
  NCBI Gene ID:4613
  NCBI Protein:NP_005369
• UniprotP04198
• Gene ID4613;
• Calculated MW 50 kDa
• Concentration 0.2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Gel: 8%SDS-PAGE
  lysate: 40 ¦Ìg, Lane: Human kidney tissue lysate,
  Primary antibody: 46618£¨MYCN Antibody) at dilution 1/200
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
  Exposure time: 20 seconds

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting